产品编号：V121010

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	V121010
名称:	Venetoclax-M27
别名:	2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(7-(4-chlorophenyl)-9,9-dimethyl-1,3,4,8,9,10,10a,11a-octahydrobenzo[e]pyrazino[2,1-b][1,3]oxazin-2(6H)-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide
CAS号:	2097938-69-5
分子量:	882.43
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Venetoclax-M27 is a derivative of Venetoclax (ABT 199), which is a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.
参考文献	Davids, M. & Letai, A.: Cancer Cell, 23, 139 (2013); Souers, A.,et al.: Nat. Med., 19, 202 (2013); Vaillant, F., et al.: Cancer Cell, 24, 120 (2013); Vogler, M., et al.: Brit. J. Haematol., 163, 139 (2013);