产品编号：V500000
产品规格：100mg
产品价格：面议
| 标准品编号: | V500000 |
| 名称: | O2-Vinyl 1-(Pyrrolidin-1-yl)diazen-1-ium-1,2-diolate |
| 别名: | 1-(Ethenyloxy)-3-(2-pyrrolidinyl)-3-(5-pyrrolidinyl)-1-triazenamine 2-oxide; 1-[(Ethenyloxy)-NNO-azoxy]-pyrrolidine; V-PYRRO/NO; |
| CAS号: | 179344-98-0 |
| 分子式: | C₆H₁₁N₃O₂ |
| 外观: | Pale Yellow Oil |
| 分子量: | 157.17 |
| 溶解度: | Ethanol |
| 稳定性: | Store in Freezer (> 1 year at -20°) |
| 类别: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | V-PYRRO/NO is a metabolically activated nitric oxide (NO) donor drug that can be used to selectively target NO delivery to the liver. The compound is metabolized by the liver, and spontaneously decomposes with a half-life of 3 seconds, liberating NO. Infusion of 30nmol/kg of V-PYRRO/NO in rats causes only a slight drop in blood pressure. At concentrations >100ug, V-PYRRO/NO increases hepatocyte viability against TNF-a-induced apoptosis by approximately 2-fold compared to cells not treated with this compound. UV/Vis: lmax: 267nm e: 9,700 |
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