产品编号：X744000

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	X744000
名称:	XAV 939
别名:	1,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one; NVP-XAV 939;
CAS号:	284028-89-3
分子式:	C₁₄H₁₁F₃N₂OS
外观:	白色至淡黄色固体
熔点:	>230°C (dec.)
分子量:	312.31
储存:	-20°C Freezer
溶解度:	DMSO (Slightly), Methanol (Very Slightly)
类别:	Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A tankyrase (TNKS) inhibitor that antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin. XAV 939 inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1.
危险品:	Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
参考文献	Huang, S. et al.: Nature, 461, 614 (2009); Wang, H. et al.: ACS Chem. Biol., 6, 192 (2011); Adles, M.E. et al.: Sci. Signal., 91, ec326 (2009);