产品编号：Z150000
产品规格：25mg
产品价格：面议
| 标准品编号: | Z150000 |
| 名称: | Zaprinast |
| 别名: | 3,6-dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one; 1,4-Dihydro-5-[2-propoxyphenyl]-7H-1,2,3-triazolo[4,5-d]pyrimidine-7-one; 8-Aza-2-(2-propoxyphenyl)-6-purinone; M&B 22,948; |
| CAS号: | 37762-06-4 |
| 分子式: | C₁₃H₁₃N₅O₂ |
| 外观: | Pale Pink to Pale Red Solid |
| 熔点: | 229-233°C (dec.) |
| 分子量: | 271.3 |
| 储存: | -20˚C Freezer |
| 溶解度: | DMSO (Slightly), Methanol (Slightly, Heated) |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | A selective inhibitor of cyclic-GMP phosphodiesterase (PDE V, calmodulin insensitive). Since cGMP mediates the vasorelaxant action of nitric oxide, as well as the natriuretic and diuretic effect of atrial natriuretic factor (ANF) through the activation of PKG (cGMP dependent protein kinase), such inhibitors may display vasodilating, relaxant, and diuretic effects. These compounds may prove useful in treating hypertension and congestive heart failure. |
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