产品编号：Z701000

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	Z701000
名称:	ZSTK 474
别名:	2-(Difluoromethyl)-1-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-1H-benzimidazole;2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-bis(morpholino)-1,3,5-triazine
CAS号:	475110-96-4
分子式:	C₁₉H₂₁F₂N₇O₂
外观:	白色固体
熔点:	212-215°C
分子量:	417.41
储存:	冰箱, under inert atmosphere
溶解度:	Chloroform, DMSO, Methanol
类别:	Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase (PI3K) isoforms. Potent PI3K inhibitor.
参考文献	Yaguchi, S., et al.: J. Natl. Cancer Inst., 98, 545 (2006); Kong, D., et al.: Cancer Sci., 98, 1638 (2007); Kong, D., et al.: Eur. J. Cancer, 45, 857 (2009); Marone, R., et al.: Mol. Cancer Res., 7, 601 (2009); Yang, S., et al.: PLoS One, 6, e26343 (2011); Haruta, K., et al.: Inflamm, Res., 61, 551 (2012);