2-脱氧-D-葡萄糖, 98%
Product Name： 2-Deoxy-D-glucose
别名:2-脱氧-D-葡萄糖 ;2-去氧-D-葡萄糖,D-2-脱氧葡萄糖
CAS号:154-17-6
分子式:C6H12O5
分子量:164.16
介绍： 溶于水和乙醇。
用途： 2-脱氧-D-葡萄糖（2-Deoxy-D-Glucose，2-DG）为天然抗代谢物类抗生素，具有能够抑制病毒感染、酵母发酵、致病菌及肿瘤细胞生长等。
熔点： 146-147 °C
特定比重： 1.533
比旋光度： 46.5 ° (C=1, H2O)
贮存： 储存温度2-8℃
生化和生理学机理： 2-Deoxy-D-Glucose (2-Deoxyglucose) is a glucose analog that inhibits glycolysis via its actions on hexokinase, the rate limiting step of glycolysis. It is phosphorylated by hexokinase to 2-DG-P which can not be further metabolized by phosphoglucose isomerase. This leads to the accumulation of 2-DG-P in the cell and the depletion in cellular ATP. In vitro, 2-Deoxyglucose has been shown to induce autophagy, increase ROS production, and activate AMPK
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