超氧化物歧化酶 来源于牛红细胞, ≥1,400 units/mg dry weight
Product Name： Superoxide Dismutase from bovine erythrocytes
别名:SOD;超氧化物;超氧化物氧化还原酶
CAS号:9054-89-1
介绍： Superoxide dismutase (SOD) catalyzes the removal of the O2- free radical. The enzyme protects oxygen-metabolizing cells against harmful effects of superoxide free-radicals. Superoxide dismutase is inactivated by H2O2. It consists of two subunits of identical molecular weight joined by a disulfide bond. The molecular weight is 32,500 daltons, and there are two Cu(II) and two Zn(II) atoms per molecule. The isoelectric point of the enzyme is 4.95.
用途： Superoxide dismutase from bovine erythrocytes has been used in a study to assess a kinetic model of radiation-induced inactivation of superoxide dismutase in nitrous oxide-saturated solutions. Superoxide dismutase from bovine erythrocytes has also been used in a study to investigate the possible participation of superoxide anion in the intestinal tryptophan 2,3-dioxygenase reaction.
贮存： 储存温度 2-8°C
生化和生理学机理： 催化超氧化物自由基的歧化反应生成过氧化氢和氧分子。在细胞防御氧自由基的毒性作用方面发挥着重要作用。与一氧化氮 (NO) 竞争超氧化物阴离子（可与 NO 反应形成过亚硝酸盐），因此 SOD 能促进 NO 的活性。在培养的大鼠卵泡、神经细胞系和转基因小鼠中，SOD 也表现出抑制细胞凋亡的作用。
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