Fumitremorgin C, 98%
Product Name: Fumitremorgin C
CAS号:118974-02-0
分子式:C22H25N3O3
分子量:379.45
介绍: Fumitremorgin C is a specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter. At 5 μM, it significantly potentiates the toxicity of the chemotherapeutic drugs mitoxantrone, doxorubicin, and topotecan in S1-M1-3.2 colon carcinoma cells. Fumitremorgin C reverses multidrug resistance in cells overexpressing BCRP but not P-glycoprotein (ABCB1) or MRP1 (ABCC1).
贮存: 储存温度:-20°C
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