Etimizol, ≥99%
Product Name： Etimizol
CAS号:64-99-3
分子式:C9H14N4O2
分子量:210.23
贮存： 储存温度-20°C
可溶性： 25°C： DMSO
生化和生理学机理：
Description：
IC50 Value： N/A
Etimizol was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain). Etimizol has a catalytic effect on the respiratory center and belongs to the group of respiratory analeptics, however, it activates adrenokortikotropnuyu pituitary function, which leads to increased levels of glucocorticosteroids in the blood. There is also evidence that short etimizol improves memory and increases mental performance.
in vitro： N/A
in vivo： The time interval between administration ofetimizol (3 mg/kg) and the onset of learning varied between 0.5 and 3 h in the several series. Etimizol did not facilitate the learning in rats whatever the time of administration and biological modality of reinforcement [1]. After administration of etimizol at doses of 10 or 1 mg/loop mean residence time of etimizol in the loop was 20.1 and 7.6 min,
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