SQ109, ≥99%
Product Name： SQ109
CAS号:502487-67-4
分子式:C22H38N2
分子量:330.55
贮存： 储存温度-20°C
可溶性： DMSO
生化和生理学机理：
SQ109 is an orally active, small molecule antibiotic for treatment of pulmonary T(tuberculosis). In Phase I clinical trials, SQ109 could replace one or more drugs in the current first-line TB drug regimen, simplify therapy, and shorten the TB treatment regimen. SQ109 has excellent in vitro activity against Mycobacterium tuberculosis within a MIC range of 1-0.5 μM (drug susceptible) and drug resistant TB bacteria, including XDR-TB, as well as potent in vivo activity against pulmonary TB alone and with other TB drugs.
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